Sodium iodoacetate
Product Specifications
UNSPSC Description
Sodium iodoacetate is a specific inhibitor of GAPDH and has glycolysis inhibitory activity. In addition, sodium iodoacetate can induce osteoarthritis and related pain models in experimental animals[1][2][3][4].
Target Antigen
Biochemical Assay Reagents
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sodium-iodoacetate.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
Smiles
O=C(O[Na])CI
Molecular Weight
207.93
References & Citations
[1]Xu, Y. et al. Glycolysis in Innate Immune Cells Contributes to Autoimmunity. Frontiers in Immunology, 13. |[2]Na, H. et al. Soluble CCR2 gene therapy controls joint inflammation, cartilage damage, and the progression of osteoarthritis by targeting MCP-1 in a monosodium iodoacetate (MIA)-induced OA rat model. Journal of Translational Medicine, 20(1)|[3]Kobayashi K, et al. Sodium iodoacetate-induced experimental osteoarthritis and associated pain model in rats[J]. Journal of Veterinary Medical Science, 2003, 65(11): 1195-1199.|[4]Güler N, et al. Sodium iodoacetate induced osteoarthrosis model in rabbit temporomandibular joint: CT and histological study (part I)[J]. International journal of oral and maxillofacial surgery, 2011, 40(11): 1289-1295.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D0849/Sodium-iodoacetate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D0849/Sodium-iodoacetate-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
305-53-3
Available Sizes
Curated Selection
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