(S) -HN0037

(S) -HN0037 is the (S) -isomer of HN0037 (HY-163529), a selective and orally active helicase-primase inhibitor that inhibits HSV replication by targeting the viral helicase-primase enzyme complex[1].

Product Specifications

CAS Number

[2233566-78-2]

UNSPSC

12352005

Target

HSV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/s-hn0037.html

Purity

98.42

Smiles

O=C(N(C1=NC(C)=C(S1)S(N)(=O)=O)C)[C@H]2CC(C=CC(C3=CC=CC=N3)=C4)=C4C2

Molecular Formula

C20H20N4O3S2

Molecular Weight

428.53

References & Citations

[1]Hou J, et al. Pharmacokinetics and Safety Study of HN0037, a Novel Anti-Human Herpes Simplex Virus Inhibitor, in Healthy Volunteers. Clin Pharmacol Drug Dev. 2022 Dec;11 (12) :1467-1473.