Cyclooctyne-O-PFP ester
Product Specifications
UNSPSC Description
Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyclooctyne-o-pfp-ester.html
Purity
95.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)COC2C#CCCCCC2
Molecular Weight
348.267
References & Citations
[1]Sun, Ying, et al. Anti-PSMA Antibodies Conjugated to Nuclear Receptor Ligand Polypeptides. 20150152187A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126518/Cyclooctyne-O-PFP-ester-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126518/Cyclooctyne-O-PFP-ester-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
886209-60-5
Available Sizes
Curated Selection
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