CMPF

CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice[1][2].

Product Specifications

CAS Number

[86879-39-2]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cmpf.html

Purity

99.57

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)CCC1=C(C(O)=O)C(C)=C(CCC)O1

Molecular Formula

C12H16O5

Molecular Weight

240.25

References & Citations

[1]Prentice KJ, et al. The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction. Cell Metab. 2014 Apr 1;19 (4) :653-66.|[2]Prentice KJ, et al. CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis. EBioMedicine. 2018 Jan;27:200-213.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GR106062-SF-2 2x 96 Well

Nori® Equine (horse) IL-5 ELISA Kit-SF-2 Plates

Ask

View Details

SR325191 1 Kit

AMN Human siRNA Oligo Duplex (Locus ID 81693)

Ask

View Details

43744161 1.0 µg

SIAH2 AAV siRNA Pooled Vector

Ask

View Details

TRC-A637635-10MG 10 mg

5Beta-Androsterone Beta-D-Glucuronide

Ask

View Details