AZD7624
AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.
Product Specifications
CAS Number
1095004-78-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; p38 MAPK
Type
Reference compound
Related Pathways
Autophagy; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/AZD7624.html
Purity
98.09
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(NC1CC1)C2=CC(N3C(C(NC4(C5=CC=CC=C5OCCNC)CC4)=NC=C3)=O)=C(C)C(F)=C2
Molecular Formula
C27H30FN5O3
Molecular Weight
491.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Pehrson R, et al. AZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic Exposure. J Pharmacol Exp Ther. 2018 Jun;365 (3) :567-572.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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