Haloxyfop

Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops[2]. Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC50 of 0.5 μM, but has no effect on this enzyme in pea[2].

Product Specifications

CAS Number

[69806-34-4]

UNSPSC

12352005

Hazard Statement

H302-H318-H412

Target

Acetyl-CoA Carboxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/haloxyfop.html

Purity

99.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(OC1=CC=C(OC2=NC=C(C(F)(F)F)C=C2Cl)C=C1)C(O)=O

Molecular Formula

C15H11ClF3NO4

Molecular Weight

361.70

Precautions

P264-P270-P273-P280-P305+P351+P338-P330-P501

References & Citations

[1]Urairat Koesukwiwat, et al. Method Development and Validation for Total Haloxyfop Analysis in Infant Formulas and Related Ingredient Matrices Using Liquid Chromatography-Tandem Mass Spectrometry. Anal Bioanal Chem|[2]J D Burton, et al. Inhibition of Plant Acetyl-Coenzyme A Carboxylase by the Herbicides Sethoxydim and Haloxyfop. Biochem Biophys Res Commun|[3]Stott W T, et al. Species-dependent induction of peroxisome proliferation by haloxyfop, an aryloxyphenoxy herbicide[J]. Toxicological Sciences, 1995, 28 (1) : 71-79.