Rabbit AntiMouse FMC63 Polyclonal Antibody (recommended for ADA assay) (MALS verified)

FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19specific CARs. So far, most of reported CART19 trials contain the antiCD19 scFv derived from FMC63, including the two FDAapproved CARs Kymriah and Yescarta.

20°C to 70°C for 12 months in lyophilized state; 70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at 20°C or lower._x000D_Please avoid repeated freezethaw cycles.

Immobilized antiCD19 antibody (Clone: FMC63) at 1 μg/mL, add increasing concentrations of Rabbit AntiMouse FMC63 Polyclonal Antibody (Cat. No. FM3S93) and then add Biotinylated antiCD19 antibody (Clone: FMC63) at 2 μg/mL. Detection was performed using HRPconjugated streptavidin with sensitivity of 78 ng/mL (QC tested).