Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Hu CD207 PE

CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.

Product Specifications

Certification

RUO

Immunogen

Fusion protein of human CD207 extracellular part and IgG Fc fragment

Target Antigen

CD207

Clone

2G3

Applications

FC (QC tested)

Format

PE

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Epaulard O, Adam L, Poux C, Zurawski G, Salabert N, Rosenbaum P, Dereuddre-Bosquet N, Zurawski S, Flamar AL, Oh S, Romain G, Chapon C, Banchereau J, Lévy Y, Le Grand R, Martinon F: Macrophage- and neutrophil-derived TNF-α instructs skin langerhans cells to prime antiviral immune responses. J Immunol. 2014 Sep 1;193 (5) :2416-26. , URL: https://pubmed.ncbi.nlm.nih.gov/25057007/, *Adam L, Tchitchek N, Todorova B, Rosenbaum P, Joly C, Poux C, Chapon C, Spetz AL, Ustav M, Le Grand R, Martinon F: Innate molecular and cellular signature in the skin preceding long-lasting T cell responses after electroporated DNA vaccination. J Immunol. 2020 Jun 15;204 (12) :3375-3388., URL: https://pubmed.ncbi.nlm.nih.gov/32385135/

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody 2G3 recognizes an extracellular/luminal epitope of CD207, a transmembrane protein selectively expressed by Langerhans cells and by some other dendritic cell subsets. This antibody clone can target vaccine-peptides to dendritic cells.

Applications Notes

6

Species

Human, Non-human primates

CAS Number

9007-83-4

Isotype

Mouse IgG1 lambda

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ARL6IP4 (ADP-ribosylation Factor-like Protein 6-interacting Protein 4, ARL-6-interacting Protein 4, Aip-4, HSP-975, HSVI-binding Protein, SR-15, SRp25, SR-25, MGC814) APC
MBS6135364-01 0.1 mL

ARL6IP4 (ADP-ribosylation Factor-like Protein 6-interacting Protein 4, ARL-6-interacting Protein 4, Aip-4, HSP-975, HSVI-binding Protein, SR-15, SRp25, SR-25, MGC814) APC

Ask
View Details
ARL6IP4 (ADP-ribosylation Factor-like Protein 6-interacting Protein 4, ARL-6-interacting Protein 4, Aip-4, HSP-975, HSVI-binding Protein, SR-15, SRp25, SR-25, MGC814) APC
MBS6135364-02 5x 0.1 mL

ARL6IP4 (ADP-ribosylation Factor-like Protein 6-interacting Protein 4, ARL-6-interacting Protein 4, Aip-4, HSP-975, HSVI-binding Protein, SR-15, SRp25, SR-25, MGC814) APC

Ask
View Details
Secalciferol 24-glucuronide
sc-473265 0.5 mg

Secalciferol 24-glucuronide

Ask
View Details
Human TMEM86A knockout cell line
ABC-KH15763 1 Vial

Human TMEM86A knockout cell line

Ask
View Details
Human TOP2b (Topoisomerase II Beta) ELISA Kit
ELK3315-01 48 Tests

Human TOP2b (Topoisomerase II Beta) ELISA Kit

Ask
View Details
Human TOP2b (Topoisomerase II Beta) ELISA Kit
ELK3315-02 96 Tests

Human TOP2b (Topoisomerase II Beta) ELISA Kit

Ask
View Details