2-Deoxy-2-fluoro-L-fucose
Product Specifications
Product Name Alternative
Adonitol-5-13C; Adonite-5-13C,Adonitol-3-13C; Adonite-3-13C
UNSPSC Description
2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-deoxy-2-fluoro-l-fucose.html
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C[C@@H](F)[C@@H]([C@@H]([C@H](C)O)O)O
Molecular Weight
166.15
References & Citations
[1]Herrera H, et al. Core-Fucosylated Tetra-Antennary N-Glycan Containing A Single N-Acetyllactosamine Branch Is Associated with Poor Survival Outcome in Breast Cancer. Int J Mol Sci. 2019;20(10):2528. Published 2019 May 23.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116705/2-Deoxy-2-fluoro-L-fucose-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116705/2-Deoxy-2-fluoro-L-fucose-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
70763-62-1
Available Sizes
Curated Selection
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