CW-069
Product Specifications
UNSPSC Description
CW-069 is an allosteric inhibitor of microtubule motor protein HSET with an IC50 of 75 μM.
Target Antigen
Kinesin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CW-069.html
Solubility
DMSO : ≥ 52 mg/mL
Smiles
O=C(NC1=CC=C(I)C=C1C(O)=O)[C@@H](NCC2=CC=CC=C2)CC3=CC=CC=C3
Molecular Weight
500.33
References & Citations
[1]Watts CA, et al. Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes. Chem Biol. 2013 Nov 21;20(11):1399-410.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15857/CW-069-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15857/CW-069-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1594094-64-0
Available Sizes
Curated Selection
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