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Jionoside D

Jionoside D is a hydroxycinnamic acid ester with antioxidant property. Jionoside D has scavenging activity of intracellular reactive oxygen species (ROS) and of DPPH radical, and lipid peroxidation inhibitory activity. Jionoside D reduces the apoptotic cells induced by H2O2 in V79-4 cells. Jionoside D increases the activities of cellular antioxidant enzymes, SOD and catalase[1][2].

Product Specifications

CAS Number

120406-34-0

UNSPSC

12352005

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/jionoside-d.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@@H](O)[C@@H](O)[C@@](O[C@@H]2[C@@H](O)[C@H](OCCC3=CC=C(OC)C(O)=C3)O[C@H](CO)[C@H]2OC(/C=C/C4=CC=C(O)C(O)=C4)=O)([H])O[C@H]1C

Molecular Formula

C30H38O15

Molecular Weight

638.61

References & Citations

[1]Sasaki H, et al. Hydroxycinnamic acid esters of phenethylalcohol glycosides from Rehmannia glutinosa var. Purpurea[J]. Phytochemistry, 1989, 28 (3) :875-879.|[2]Chae S, et al. Antioxidant activity of jionoside D from Clerodendron trichotomum. Biol Pharm Bull. 2004 Oct;27 (10) :1504-8.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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