Xanthurenic acid

Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus.

Product Specifications

CAS Number

[59-00-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Endogenous Metabolite; mGluR

Type

Natural Products

Related Pathways

Apoptosis; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/4,8-Dihydroxyquinoline-2-carboxylic_acid.html

Purity

99.94

Solubility

1 M NaOH : 33.33 mg/mL (ultrasonic) |DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=NC2=C(O)C=CC=C2C(O)=C1)O

Molecular Formula

C10H7NO4

Molecular Weight

205.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Copeland CS, et al. Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Neuropharmacology. 2013 Mar;66:133-42.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite; mGluR2; mGluR3

Available Sizes

Curated Selection

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