XQ2B
Product Specifications
UNSPSC Description
XQ2B is a cGAS inhibitor targeting protein-DNA interactions and phase separation. XQ2B inhibits herpes simplex virus 1 (HSV-1)-induced antiviral immune responses and enhances HSV-1 infection in vitro and in vivo[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xq2b.html
Purity
99.19
Solubility
10 mM in DMSO
Smiles
O=C([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H]1N(C([C@@H](CC2=CC=CC=C2)NC([C@H](CC(C)C)NC([C@@H](N3)CCCNC(N)=N)=O)=O)=O)CCC1)=O)=O)=O)N[C@@H](C(N[C@@H](C)C(N[C@]([C@H](O)C)([H])C3=O)=O)=O)CC4=CC=CC=C4
Molecular Weight
1201.46
References & Citations
[1]Wang X, et al. Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation. Nat Commun. 2023 Oct 2;14(1):6132.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P5997/XQ2B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P5997/XQ2B-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2104728-28-9
Available Sizes
Curated Selection
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