Ompenaclid
Ompenaclid (RGX-202) is an oral small-molecule SLC6A8 transporter inhibitor. Ompenaclid robustly inhibits creatine import in vitro and in vivo, reduces intracellular phosphocreatine and ATP levels, and induces tumor apoptosis. Ompenaclid can be used for the research of cancer and duchenne muscular dystrophy[1][2].
Product Specifications
CAS Number
353-09-3
Product Name Alternative
RGX-202; 3-Guanidinopropionic acid
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Apoptosis; Endogenous Metabolite
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ompenaclid.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : ≥ 50 mg/mL
Smiles
O=C(O)CCNC(N)=N
Molecular Formula
C4H9N3O2
Molecular Weight
131.14
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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