What is the catalog number for Rat EphA2 Protein, His Tag (MALS verified)?

The catalog number for Rat EphA2 Protein, His Tag (MALS verified) is EP2-R52H5-100ug.

What sizes are available for Rat EphA2 Protein, His Tag (MALS verified)?

Rat EphA2 Protein, His Tag (MALS verified) is available in the following size(s): 100 µg.

Is Rat EphA2 Protein, His Tag (MALS verified) in stock?

Rat EphA2 Protein, His Tag (MALS verified) is currently made to order / not held in immediate stock. Contact us for lead time.

What are the weight and dimensions of Rat EphA2 Protein, His Tag (MALS verified)?

Rat EphA2 Protein, His Tag (MALS verified) has the following package details: 100ug*1.

Who manufactures Rat EphA2 Protein, His Tag (MALS verified)?

Rat EphA2 Protein, His Tag (MALS verified) is manufactured by CRB.

What is the estimated delivery time for Rat EphA2 Protein, His Tag (MALS verified)?

Estimated delivery time for Rat EphA2 Protein, His Tag (MALS verified) is approximately 10 business day(s), depending on your location.

Rat EphA2 Protein, His Tag (MALS verified)

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EF1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. Engaged by the ligand ephrin-A5/EF5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EF2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.6 kDa. The protein migrates as 60-67 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

D3ZBN3

Expression Region

Gln 24 - Met 536

Host

HEK293

Target

EphA2

Conjugation

Unconjugated

Tag

C-10xHis

Source

Rat

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Human Ephrin-A1, Fc Tag (Cat. No. EF1-H5251) at 5 μg/mL (100 μL/well) can bind Rat EphA2 Protein, His Tag (Cat. No. EP2-R52H5) with a linear range of 0.01-0.156 (QC tested).