D-Erythro-dihydrosphingosine
D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.
Product Specifications
CAS Number
[764-22-7]
Product Name Alternative
Sphinganine (d18:0)
UNSPSC
12352211
Hazard Statement
H302, H315, H319
Target
Endogenous Metabolite; Phospholipase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/D-Erythro-dihydrosphingosine.html
Purity
99.55
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 50 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO
Molecular Formula
C18H39NO2
Molecular Weight
301.51
Precautions
H302, H315, H319
References & Citations
[1]Nakamura H, et al. Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine. Eur J Pharmacol. 2004 Jan 19;484 (1) :9-17.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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