MBP146-78
MBP146-78 is a potent and selective inhibitor of cGMP dependent protein kinases.
Product Specifications
CAS Number
[188343-77-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/MBP146-78.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN1CCC(C2=CC(C3=CC=NC=C3)=C(C4=CC=C(F)C=C4)N2)CC1
Molecular Formula
C21H22FN3
Molecular Weight
335.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Nare B, et al. Evaluation of a cyclic GMP-dependent protein kinase inhibitor in treatment of murine toxoplasmosis: gamma interferon is required for efficacy. Antimicrob Agents Chemother. 2002 Feb;46 (2) :300-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Toxoplasma
Available Sizes
Curated Selection
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