SIRT2-IN-14
SIRT2-IN-14 (Compound 78) is a selectve inhibitor for SIRT2 with an IC50 of 0.196 μM[1].
Product Specifications
CAS Number
1884571-59-8
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sirt2-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC(COC2=CN=CC(C(N)=O)=C2)=C1)C(C=C3)=CC=C3OC4=CC=CC=C4
Molecular Formula
C26H21N3O4
Molecular Weight
439.46
References & Citations
[1]Ai T, et al., 5- ((3-Amidobenzyl) oxy) nicotinamides as Sirtuin 2 Inhibitors. J Med Chem. 2016 Apr 14;59 (7) :2928-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT1; SIRT2; SIRT3
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