8-Dehydrocholesterol
8-Dehydrocholesterol elevated concentration is one of the diagnostic biochemical hallmarks of classical Smith-Lemli-Opitz syndrome (SLOS) .
Product Specifications
CAS Number
[70741-38-7]
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/8-Dehydrocholesterol.html
Purity
95.61
Solubility
DMSO : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])C3=C([C@@]4(C(C[C@@H](O)CC4)=CC3)C)CC1
Molecular Formula
C27H44O
Molecular Weight
384.64
References & Citations
[1]Batta AK, et al. Identification of 8-dehydrocholesterol (cholesta-5,8-dien-3 beta-ol) in patients with Smith-Lemli-Opitz syndrome. J Lipid Res. 1995 Apr;36 (4) :705-13.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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