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8-Dehydrocholesterol

8-Dehydrocholesterol elevated concentration is one of the diagnostic biochemical hallmarks of classical Smith-Lemli-Opitz syndrome (SLOS) .

Product Specifications

CAS Number

[70741-38-7]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/8-Dehydrocholesterol.html

Purity

95.61

Solubility

DMSO : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])C3=C([C@@]4(C(C[C@@H](O)CC4)=CC3)C)CC1

Molecular Formula

C27H44O

Molecular Weight

384.64

References & Citations

[1]Batta AK, et al. Identification of 8-dehydrocholesterol (cholesta-5,8-dien-3 beta-ol) in patients with Smith-Lemli-Opitz syndrome. J Lipid Res. 1995 Apr;36 (4) :705-13.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

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