Pumecitinib
Pumecitinib is a Janus kinase (JAK) inhibitor. Pumecitinib shows anti-inflammatory activity[1].
Product Specifications
CAS Number
[2401057-12-1]
Product Name Alternative
PG-011
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pumecitinib.html
Purity
99.81
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CCC1(CN(S(=O)(C(C)C)=O)C1)N2N=C(C(C3=C4C=CNC4=NC=N3)=C2)N
Molecular Formula
C17H20N8O2S
Molecular Weight
400.46
References & Citations
[1]WHO Drug Information-World Health Organization (WHO) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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