TRV056
TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R) . TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists[1].
Product Specifications
CAS Number
[812644-79-4]
UNSPSC
12352209
Target
Angiotensin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/trv056.html
Purity
99.91
Solubility
H2O : 1.96 mg/mL (ultrasonic; adjust pH to 2 with HCl)
Smiles
Molecular Formula
C52H74N14O13
Molecular Weight
1103.23
References & Citations
[1]Laura M Wingler, et al. Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations. Cell. 2019 Jan 24;176 (3) :468-478.e11.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
AT1 Receptor
Available Sizes
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