Diketone-PEG4-Biotin

Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2353409-85-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/diketone-peg4-biotin.html

Purity

95.0

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NCCOCCOCCOCCOCCC(NC1=CC=C(CCC(CC(C)=O)=O)C=C1)=O)CCCC[C@H]2[C@](NC3=O)([H])[C@](N3)([H])CS2

Molecular Formula

C33H50N4O9S

Molecular Weight

678.84

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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