Diketone-PEG4-Biotin
Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2353409-85-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/diketone-peg4-biotin.html
Purity
95.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NCCOCCOCCOCCOCCC(NC1=CC=C(CCC(CC(C)=O)=O)C=C1)=O)CCCC[C@H]2[C@](NC3=O)([H])[C@](N3)([H])CS2
Molecular Formula
C33H50N4O9S
Molecular Weight
678.84
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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