DB07268

DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

Product Specifications

CAS Number

[929007-72-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

JNK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/DB07268.html

Concentration

10mM

Purity

99.49

Solubility

DMSO : ≥ 32 mg/mL

Smiles

O=C(N)C1=CC=CC=C1NC2=NC(NC3=CC=CC(O)=C3)=NC=C2

Molecular Formula

C17H15N5O2

Molecular Weight

321.33

Precautions

H302, H315, H319

References & Citations

[1]Liu M, et al. Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17 (3) :668-72.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

JNK1

Available Sizes

Curated Selection

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