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DB07268

Product Specifications

UNSPSC Description

DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

Target Antigen

JNK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/DB07268.html

Solubility

DMSO : ≥ 32 mg/mL

Smiles

O=C(N)C1=CC=CC=C1NC2=NC(NC3=CC=CC(O)=C3)=NC=C2

Molecular Weight

321.33

References & Citations

[1]Liu M, et al. Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17(3):668-72.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-15737/DB07268-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-15737/DB07268-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

929007-72-7

Available Sizes

Curated Selection

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