DB07268
DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.
Product Specifications
CAS Number
[929007-72-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
JNK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/DB07268.html
Concentration
10mM
Purity
99.49
Solubility
DMSO : ≥ 32 mg/mL
Smiles
O=C(N)C1=CC=CC=C1NC2=NC(NC3=CC=CC(O)=C3)=NC=C2
Molecular Formula
C17H15N5O2
Molecular Weight
321.33
Precautions
H302, H315, H319
References & Citations
[1]Liu M, et al. Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17 (3) :668-72.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JNK1
Available Sizes
Curated Selection
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