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DR-4004

DR-4004 is a 5-HT7 receptor antagonist that attenuates the decreased level of performance produced by mCPP and the performance levels after p-chloroamphetamine (PCA) lesion of the 5-HT system. DR-4004 also reverses amnesia induced by Scopolamine (HY-N0296) and Dizocilpine (HY-15084B) . DR-4004 is promising for research of schizophrenia, cognitive deficits and atypical antipsychotic agents[1].

Product Specifications

CAS Number

[201608-41-5]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dr-4004.html

Smiles

O=C1NC2=C3C1(CCCC3=CC=C2)CCCCN4CC=C(CC4)C5=CC=CC=C5

Molecular Formula

C26H30N2O

Molecular Weight

386.53

References & Citations

[1]Meneses A. Effects of the 5-HT7 receptor antagonists SB-269970 and DR 4004 in autoshaping Pavlovian/instrumental learning task. Behav Brain Res. 2004 Dec 6;155 (2) :275-82.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT7 Receptor

Curated Selection

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