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ALPK1-IN-3

Product Specifications

CAS Number

2765633-73-4

UNSPSC Description

ALPK1-IN-3 is an inhibitor of ALPK1 extracted from patent WO2022063153A1 compound T007. ALPK1-IN-3 inhibits kidney proinflammatory gene expression and improves the survival rate of the animals in sepsis induced acute kidney injury animal model[1]. ALPK1-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Target Antigen

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/alpk1-in-3.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(C=C(N2CCNCC2)C=C1F)F)NC3=NC4=C(S3)C=CC=C4C#C

Molecular Weight

398.43

References & Citations

[1]Danyang Liu, et.al. Benzothiazole and quinoline derivatives and their use.

Shipping Conditions

Room Temperature

Clinical Information

No Development Reported

Available Sizes

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