ALPK1-IN-3
Product Specifications
CAS Number
2765633-73-4
UNSPSC Description
ALPK1-IN-3 is an inhibitor of ALPK1 extracted from patent WO2022063153A1 compound T007. ALPK1-IN-3 inhibits kidney proinflammatory gene expression and improves the survival rate of the animals in sepsis induced acute kidney injury animal model[1]. ALPK1-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alpk1-in-3.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C=C(N2CCNCC2)C=C1F)F)NC3=NC4=C(S3)C=CC=C4C#C
Molecular Weight
398.43
References & Citations
[1]Danyang Liu, et.al. Benzothiazole and quinoline derivatives and their use.
Shipping Conditions
Room Temperature
Clinical Information
No Development Reported
Available Sizes
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