Purified Anti-Human CD45 Antibody[BC8]

CD45, previously called LCA (leukocyte common antigen), T200, or Ly5 in mice, is member C of the class 1 (receptor‑like) protein tyrosine phosphatase family (PTPRC) . It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin . Multiple splicing isoforms of exon 4 (A), 5 (B), and 6 (C) are expressed according to cell type, developmental stage and antigenic exposure . The longest form, CD45RABC (called B220 in mouse) is expressed on B lymphocytes, The shortest form, CD45R0, lacking exons 4, 5 and 6 which encode aa 34‑194, is expressed on memory cells, while intermediate sizes are expressed on other T cells.

B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; PTPRC; CD45 antigen; CD45R0; Ly-5; protein tyrosine phosphatase; receptor type; Receptor-type tyrosine-protein phosphatase C; CD45RO; Receptor-type tyrosine-protein phosphatase CLeukocyte common antigen (L-CA) ; T200; c polypeptide; CD 45; homolog of; Leukocyte common antigen; loc; Lyt-4; OTTHUMP00000033813; OTTHUMP00000033816; OTTHUMP00000033817; OTTHUMP00000038574; Protein tyrosine phosphatase receptor type c polypeptide; protein tyrosine phosphatase; receptor type; C; receptor type C; T200 glycoprotein; T200 leukocyte common antigen; B220; CD45; CD45 antigen; CD45R; GP180; L-CA; LCA; Ly-5; LY5; Protein tyrosine phosphatase; receptor type; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200