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Pegaptanib (sodium)

Pegaptanib sodium is an RNA aptamer with polyethylene glycol modifications, which is directed against vascular endothelial growth factor (VEGF) -165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) [1].

Product Specifications

CAS Number

[222716-86-1]

Product Name Alternative

EYE001; NX1838

UNSPSC

12352208

Target

VEGFR

Type

Oligonucleotides

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pegaptanib-sodium.html

Purity

90.51

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

[Pegaptanib(sodium)]

Molecular Formula

C294H342F13N107Na28O188P28[C2H4O]n

Molecular Weight

50000 (Approximately)

References & Citations

[1]Eugene W M Ng, et al. Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat Rev Drug Discov. 2006 Feb;5 (2) :123-32.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Oligonucleotides

Clinical Information

Launched

Available Sizes

Curated Selection

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