RWJ 22108
RWJ 22108 is a bronchoselective calcium channel blocker, with the IC50 of 5.7 nM in calcium-dependent contraction of canine bronchiolar smooth muscle[1].
Product Specifications
CAS Number
112769-37-6
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/rwj-22108.html
Smiles
O=C(OCCN(CC1=CC=CC=C1)C)C2=C(NC(CCCC3)=C(C2C4=C(C=CC=C4Cl)F)S3(=O)=O)C
Molecular Formula
C27H30ClFN2O4S
Molecular Weight
533.05
References & Citations
[1]J B Moore Jr, et al. RWJ-22108--a novel airway tissue--selective calcium channel blocker. Agents Actions. 1993 Sep;40 (1-2) :57-61.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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