AD 4743
AD 4743 (ADD 4743) is a metabolite of Ciglitazone. AD 4743 is an adipogenic agent. AD 4743 induces FPRP accumulation and accumulation of lipid droplets. AD 4743 inhibits cell proliferation of preadipose cells[1][2].
Product Specifications
CAS Number
87858-57-9
Product Name Alternative
ADD 4743
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ad-4743.html
Smiles
O=C(N1)SC(CC2=CC=C(OCC3(C)CC(O)CCC3)C=C2)C1=O
Molecular Formula
C18H23NO4S
Molecular Weight
349.44
References & Citations
[1]Orlicky DJ, et al. Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells. J Lipid Res. 1998 Jun;39 (6) :1152-61.|[2]Hiragun A, et al. Preadipocyte differentiation in vitro: identification of a highly active adipogenic agent. J Cell Physiol. 1988 Jan;134 (1) :124-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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