AD 4743

AD 4743 (ADD 4743) is a metabolite of Ciglitazone (HY-W011220) . AD 4743 is an adipogenic agent. AD 4743 induces FPRP accumulation and accumulation of lipid droplets. AD 4743 inhibits cell proliferation of preadipose cells[1][2].

Product Specifications

CAS Number

[87858-57-9]

Product Name Alternative

ADD 4743

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ad-4743.html

Smiles

O=C(N1)SC(CC2=CC=C(OCC3(C)CC(O)CCC3)C=C2)C1=O

Molecular Formula

C18H23NO4S

Molecular Weight

349.44

References & Citations

[1]Orlicky DJ, et al. Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells. J Lipid Res. 1998 Jun;39 (6) :1152-61.|[2]Hiragun A, et al. Preadipocyte differentiation in vitro: identification of a highly active adipogenic agent. J Cell Physiol. 1988 Jan;134 (1) :124-30.