Xenin

Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake.

Product Specifications

CAS Number

[144092-28-4]

UNSPSC

12352209

Target

Endogenous Metabolite

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Xenin.html

Purity

99.25

Solubility

H2O

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CNC=N3)C(N4[C@@H](CCC4)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N5[C@@H](CCC5)C(N[C@@H](CC6=CNC7=CC=CC=C67)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N

Molecular Formula

C139H224N38O32S

Molecular Weight

2971.57

References & Citations

[1]Cooke JH, et al. Peripheral and central administration of xenin and neurotensin suppress food intake in rodents. Obesity (Silver Spring) . 2009 Jun;17 (6) :1135-43.|[2]Leckstrom A, et al. Xenin, a gastrointestinal peptide, regulates feeding independent of the melanocortinsignaling pathway. Diabetes. 2009 Jan;58 (1) :87-94.|[3]Kim ER, et al. Xenin delays gastric emptying rate and activates the brainstem in mice. Neurosci Lett. 2010 Aug 30;481 (1) :59-63.