Isocorydine
Isocorydine is isolated from Dicranostigma leptopodum (Maxim.) Fedde (DLF) . Isocorydine combines with Doxorubicin (DOX) has a promising potential to eradicate hepatocellular carcinoma (HCC) [1].
Product Specifications
CAS Number
475-67-2
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/isocorydine.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
COC1=C2C3=C(C=C1OC)CCN(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C24
Molecular Formula
C20H23NO4
Molecular Weight
341.40
Precautions
H302, H312, H332
References & Citations
[1]Pan JX, et al. Isocorydine suppresses doxorubicin-induced epithelial-mesenchymal transition via inhibition of ERK signaling pathways in hepatocellular carcinoma. Am J Cancer Res. 2018 Jan 1;8 (1) :154-164. eCollection 2018.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
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