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Estradiol 17- (β-D-Glucuronide) (sodium)

Estradiol 17- (β-D-Glucuronide) sodium, a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans[1].

Product Specifications

CAS Number

[15087-02-2]

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H351

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/estradiol-17-β-d-glucuronide-sodium.html

Purity

99.46

Solubility

DMSO : 50 mg/mL (ultrasonic; adjust pH to 3 with 1 M HCl)

Smiles

C[C@@]12[C@](CC[C@@H]2O[C@]3([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O[Na])=O)([H])[C@@]4([H])[C@](C5=C(C=C(O)C=C5)CC4)([H])CC1

Molecular Formula

C24H31NaO8

Molecular Weight

470.49

Precautions

H302+H312+H332, H351

References & Citations

[1]Kinbara S, et al. Improvement of estradiol-17 beta-D-glucuronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats. Scand J Gastroenterol. 1997;32 (9) :947-952.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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