Terminal deoxyribonucleotidyltransferase
Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V (D) J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells[1].
Product Specifications
CAS Number
9027-67-2
Product Name Alternative
TdT
UNSPSC
12352204
Target
DNA/RNA Synthesis
Type
Enzyme
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/terminal-deoxyribonucleotidyltransferase.html
Solubility
10 mM in DMSO
Smiles
[Terminaldeoxyribonucleotidyltransferase]
References & Citations
[1]Boulé JB, et, al. Terminal deoxynucleotidyl transferase indiscriminately incorporates ribonucleotides and deoxyribonucleotides. J Biol Chem. 2001 Aug 17;276 (33) :31388-93.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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