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Terminal deoxyribonucleotidyltransferase

Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V (D) J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells[1].

Product Specifications

CAS Number

9027-67-2

Product Name Alternative

TdT

UNSPSC

12352204

Target

DNA/RNA Synthesis

Type

Enzyme

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others; Cancer

Assay Protocol

https://www.medchemexpress.com/terminal-deoxyribonucleotidyltransferase.html

Solubility

10 mM in DMSO

Smiles

[Terminaldeoxyribonucleotidyltransferase]

References & Citations

[1]Boulé JB, et, al. Terminal deoxynucleotidyl transferase indiscriminately incorporates ribonucleotides and deoxyribonucleotides. J Biol Chem. 2001 Aug 17;276 (33) :31388-93.

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20°C for 2 years

Scientific Category

Enzyme

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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