Communic acid
Communic acid ((+) -Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging[1][2][3].
Product Specifications
CAS Number
2761-77-5
Product Name Alternative
(+) -Communic acid
UNSPSC
12352211
Target
Akt; Bacterial; MMP
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/communic-acid.html
Solubility
10 mM in DMSO
Smiles
C[C@@]1([C@H]2C/C=C(C)/C=C)[C@](CCC2=C)([H])[C@](C)(CCC1)C(O)=O
Molecular Formula
C20H30O2
Molecular Weight
302.45
References & Citations
[1]Samoylenko V, et al. Antiparasitic, nematicidal and antifouling constituents from Juniperus berries. Phytother Res. 2008;22 (12) :1570-1576.|[2]Huh WB, et al. Brown Pine Leaf Extract and Its Active Component Trans-Communic Acid Inhibit UVB-Induced MMP-1 Expression by Targeting PI3K. PLoS One. 2015;10 (6) :e0128365. Published 2015 Jun 11.|[3]Carpenter CD, et al. Anti-mycobacterial natural products from the Canadian medicinal plant Juniperus communis. J Ethnopharmacol. 2012;143 (2) :695-700.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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