WM-662
WM-662 is a WDR5-MYC interaction inhibitor, with an IC50 of 18 μM. WM-662 has potential for the research of cancer, aging, and neurodegenerative disorders[1].
Product Specifications
CAS Number
[1308257-47-7]
UNSPSC
12352005
Target
WDR5
Type
Reference compound
Related Pathways
Epigenetics
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/wm-662.html
Purity
99.48
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@H](O[C@@H](CC1=CC=C(C2=CC=CC(Cl)=C2)C=C1)C(NC3=NN=NN3)=O)C(O)=O
Molecular Formula
C19H18ClN5O4
Molecular Weight
415.83
References & Citations
[1]Ding J, et, al. Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. ACS Chem Biol. 2023 Jan 20;18 (1) :34-40.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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