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WM-662

WM-662 is a WDR5-MYC interaction inhibitor, with an IC50 of 18 μM. WM-662 has potential for the research of cancer, aging, and neurodegenerative disorders[1].

Product Specifications

CAS Number

[1308257-47-7]

UNSPSC

12352005

Target

WDR5

Type

Reference compound

Related Pathways

Epigenetics

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/wm-662.html

Purity

99.48

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@H](O[C@@H](CC1=CC=C(C2=CC=CC(Cl)=C2)C=C1)C(NC3=NN=NN3)=O)C(O)=O

Molecular Formula

C19H18ClN5O4

Molecular Weight

415.83

References & Citations

[1]Ding J, et, al. Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. ACS Chem Biol. 2023 Jan 20;18 (1) :34-40.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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