Recombinant Human CDK1 & Cyclin A2 Protein (Full Length, GST Tag, Active)

<strong>Recombinant Human CDK1 &amp; Cyclin A2 Protein (Full Length, GST Tag, Active)</strong>_x000D_ <strong>Catalog number:</strong> B2018981_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> CDK1 ~59 kDa; CyclinA2 ~78 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> Recombinant Human CDK1 &amp; Cyclin A2 Protein (Full Length, GST Tag), Active_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kanakkanthara A, Jeganathan KB, Limzerwala JF, Baker DJ, Hamada M, Nam HJ, van Deursen WH, Hamada N, Naylor RM, Becker NA, Davies BA, van Ree JH, Mer G, Shapiro VS, Maher LJ 3rd, Katzmann DJ, van Deursen JM. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation Science. 2016 Sep 30;353(6307):1549-1552._x000D_ 2: Silva Cascales H, Burdova K, Middleton A, Kuzin V, Müllers E, Stoy H, Baranello L, Macurek L, Lindqvist A. Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1 Life Sci Alliance. 2021 Jan 5;4(3):e202000980._x000D_ 3: Katsuno Y, Suzuki A, Sugimura K, Okumura K, Zineldeen DH, Shimada M, Niida H, Mizuno T, Hanaoka F, Nakanishi M. Cyclin A-Cdk1 regulates the origin firing program in mammalian cells Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3184-9._x000D_ 4: Ma HT, Tsang YH, Marxer M, Poon RY. Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosis Mol Cell Biol. 2009 Dec;29(24):6500-14._x000D_ 5: Luo P, Tresini M, Cristofalo V, Chen X, Saulewicz A, Gray MD, Banker DE, Klingelhutz AL, Ohtsubo M, Takihara Y, Norwood TH. Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors Exp Cell Res. 2004 Apr 1;294(2):406-19._x000D_ 6: Vitrat N, Cohen-Solal K, Pique C, Le Couedic JP, Norol F, Larsen AK, Katz A, Vainchenker W, Debili N. Endomitosis of human megakaryocytes are due to abortive mitosis Blood. 1998 May 15;91(10):3711-23._x000D_ 7: Vera J, Jaumot M, Estanyol JM, Brun S, Agell N, Bachs O. Heterogeneous nuclear ribonucleoprotein A2 is a SET-binding protein and a PP2A inhibitor Oncogene. 2006 Jan 12;25(2):260-70._x000D_ 8: Boratyn E, Nowak I, Karnas E, Ryszawy D, Wnuk D, Polus A, Durbas M, Horwacik I, Rokita H. MCPIP1 overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block J Cell Biochem. 2020 Jun;121(5-6):3406-3425._x000D_ 9: Badie C, Itzhaki JE, Sullivan MJ, Carpenter AJ, Porter AC. Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells Mol Cell Biol. 2000 Apr;20(7):2358-66._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15070768">10: Farrell CJ, Lee JM, Shin EC, Cebrat M, Cole PA, Hayward SD. Inhibition of Epstein-Barr virus-induced growth proliferation by a nuclear antigen EBNA2-TAT peptide Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4625-30. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human CDK1 &amp; Cyclin A2 Protein (Full Length, GST Tag, Active) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>