Anti-melanoma agent 3

Anti-melanoma agent 3 (compound 5cb) is a 2-aryl-4-benzoyl-imidazole (ABI) derivative and an inhibitor of melanoma xenogeneic tumors. Anti-melanoma agent 3 exerts anticancer activity by interacting with the colchicine binding site to inhibit tubulin polymerization[1].

Product Specifications

CAS Number

[1253697-49-2]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anti-melanoma-agent-3.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(F)C=C1)C2=CN=C(C3=CC=C(OC)C=C3)N2

Molecular Formula

C17H13FN2O2

Molecular Weight

296.30

References & Citations

[1]Chen J, et al. Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents. J Med Chem. 2010 Oct 28;53 (20) :7414-27.