Anti-melanoma agent 3
Anti-melanoma agent 3 (compound 5cb) is a 2-aryl-4-benzoyl-imidazole (ABI) derivative and an inhibitor of melanoma xenogeneic tumors. Anti-melanoma agent 3 exerts anticancer activity by interacting with the colchicine binding site to inhibit tubulin polymerization[1].
Product Specifications
CAS Number
[1253697-49-2]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anti-melanoma-agent-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(F)C=C1)C2=CN=C(C3=CC=C(OC)C=C3)N2
Molecular Formula
C17H13FN2O2
Molecular Weight
296.30
References & Citations
[1]Chen J, et al. Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents. J Med Chem. 2010 Oct 28;53 (20) :7414-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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