STING ligand-1
STING ligand-1 is a lead STING ligand with an IC50 of 68 nM for HAQ STING[1].
Product Specifications
CAS Number
2365039-41-2
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/STING_ligand-1.html
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=CC(F)=CC=C2[C@H](CC(O)=O)[C@@H](C3=CC(OCCO4)=C4C=C3)N1C5=CC(Cl)=C(C(C)(C)C)C=C5
Molecular Formula
C29H27ClFNO5
Molecular Weight
523.98
References & Citations
[1]Siu T, et al. Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING. ACS Med Chem Lett. 2018 Dec 6;10 (1) :92-97.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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