ITGAE (heavy chain, Cleaved-Ala179) rabbit pAb
Integrin subunit alpha E (ITGAE) Homo sapiens Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P38570
Swiss Prot
P38570
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human ITGAE (heavy chain, Cleaved-Ala179)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
110 128kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
110 128kD
Fragment
IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
Gene ID (Human)
3682
Available Sizes
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