20-Hydroxyganoderic Acid G
Product Specifications
UNSPSC Description
20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the agent discovery of nerve inflammation diseases associated with microglia activated by LPS[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/20-hydroxyganoderic-acid-g.html
Solubility
10 mM in DMSO
Smiles
CC1(C)[C@@H](O)CC[C@]2(C)C3=C([C@@]4(C(C[C@@H]([C@]4([C@H](O)C3=O)C)[C@@](C)(O)CC(CC(C)C(O)=O)=O)=O)C)[C@@H](O)C[C@@]12[H]
Molecular Weight
548.66
References & Citations
[1]Jiao Y, et al. Lanostane triterpenoids from <i>Ganoderma curtisii</i> and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7018/20-Hydroxyganoderic-Acid-G-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7018/
Clinical Information
No Development Reported
CAS Number
400604-12-8
Available Sizes
Curated Selection
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