Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

(R) -Zunsemetinib

Selected Variant

HY-139553A-01

Size: 1 mg

(R) -Zunsemetinib is the isomer of Zunsemetinib , and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases[1].

Product Specifications

CAS Number

1640282-44-5

Product Name Alternative

(R) -ATI-450; (R) -CDD-450

UNSPSC

12352005

Target

Drug Isomer

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/r-zunsemetinib.html

Purity

97.84

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

FC1=CC(F)=CN=C1COC2=C(Cl)C(N(C3=CC(C4=NC(C(C)(C)O)=NC=C4)=NC=C3C)C(C)=C2)=O

Molecular Formula

C25H22ClF2N5O3

Molecular Weight

513.92

References & Citations

[1]Zunsemetinib (ATI-450) – Investigational oral MK2 pathway inhibitor|[2]Aclaris Therapeutics Announces ATI-450 (MK2 pathway Inhibitor) publication in Journal of Experimental Medicine|[3]Wang C, et al. Selective inhibition of the p38α MAPK-MK2 axis inhibits inflammatory cues including inflammasome priming signals. J Exp Med. 2018;215 (5) :1315-1325.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Gastrin (GAST/2635), CF488A conjugate, 0.1mg/mL
BNC882635-500 1x 500 µL

Gastrin (GAST/2635), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Insulin (E2-E3), CF568 conjugate, 0.1mg/mL
BNC680281-500 1x 500 µL

Insulin (E2-E3), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD86 (C86/1146), CF488A conjugate, 0.1mg/mL
BNC881146-500 1x 500 µL

CD86 (C86/1146), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
HCG-intact (HCGab/52), CF740 conjugate, 0.1mg/mL
BNC740052-500 1x 500 µL

HCG-intact (HCGab/52), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details