FAUC 365
Product Specifications
UNSPSC Description
FAUC 365 is a highly dopamine D3 receptor-selective antagonist with Ki values of 0.5 nM, 340, 2600, and 3600 nM at D3, D4.4, D2short, and D2Long receptors, respectively. FAUC 365 can be used for the research of schizophrenia, and Parkinson's disease[1][2].
Target Antigen
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fauc-365.html
Purity
98.75
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
ClC1=C(C(N2CCN(CC2)CCCCNC(C3=CC4=C(S3)C=CC=C4)=O)=CC=C1)Cl
Molecular Weight
462.44
References & Citations
[1]Philip Seeman, et al. Dopamine D2 and D3 receptors in human putamen, caudate nucleus, and globus pallidus. Synapse. 2006 Sep 1;60(3):205-11.|[2]Carsten Hocke, et al. Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3963-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116020/FAUC-365-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116020/FAUC-365-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
474432-66-1
Available Sizes
Curated Selection
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