p,p'-DDE (Standard)
Product Specifications
UNSPSC Description
p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[1].
Target Antigen
Androgen Receptor; Drug Metabolite
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/p-p-dde-standard.html
Smiles
Cl/C(Cl)=C(C1=CC=C(Cl)C=C1)/C2=CC=C(Cl)C=C2
Molecular Weight
318.03
References & Citations
[1]Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1986R/p-p-DDE-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1986R/
CAS Number
72-55-9
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