(RS) -AMPA (hydrochloride)
(RS) -AMPA ((±) -AMPA) hydrochloride is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS) -AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
Product Specifications
CAS Number
2922283-04-1
Product Name Alternative
(±) -AMPA (hydrochloride)
UNSPSC
12352211
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rs-ampa-hydrochloride.html
Purity
98.74
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1NOC(C)=C1CC(C(O)=O)N.Cl
Molecular Formula
C7H11ClN2O4
Molecular Weight
222.63
References & Citations
[1]Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36 (1) :59-62. |[2]Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249 (4976) :1580-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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