(RS) -AMPA (hydrochloride)

(RS) -AMPA ((±) -AMPA) hydrochloride is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS) -AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].

Product Specifications

CAS Number

[2922283-04-1]

Product Name Alternative

(±) -AMPA (hydrochloride)

UNSPSC

12352211

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rs-ampa-hydrochloride.html

Purity

98.74

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1NOC(C)=C1CC(C(O)=O)N.Cl

Molecular Formula

C7H11ClN2O4

Molecular Weight

222.63

References & Citations

[1]Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36 (1) :59-62. |[2]Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249 (4976) :1580-5.